toll-likereceptor4相关论文
目的:泌乳素瘤危害人体健康,其发病机制尚不清楚,目前国内上市药物仅溴隐亭一种,且易发生耐药现象。此外,女性发病率远高于男性,尤......
目的:S100钙结合蛋白A8（S100 calcium-binding protein A8,S100A8）又称巨噬细胞相关蛋白8（Macrophage-related 8,MRP8）,它参与了创伤性......
目的:探讨Toll样受体4（TLR4）通路在脓毒症大鼠心肌损伤和心功能障碍中的作用。方法:将18只雄性SD大鼠按照随机数字表法分为对照组、......
背景周期性机械牵拉是机械通气诱导肺损伤的一个重要的病因学元素,同时机械牵拉中细胞因子的变化引起远端肺组织渗透性的改变从而......
Bupleurum polysaccharides ameliorated renal injury in diabetic mice associated with suppression of H
Bupleurum polysaccharides (BPs) is isolated from Bupleurum smithii var.parvifolium,a key traditional Chinese medicine.Th......
Toll-like receptor 4-mediated nuclear factor-KB activation in spinal cord contributes to chronic mor
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Toll-Like Receptor 4 Deficiency Causes Reduced Exploratory Behavior in Mice Under Approach-Avoidance
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Haplotype Analysis of TLR4 Gene and Its Effects on Milk Somatic Cell Score in Chinese Commercial Cat
Bovine mastitis is a very complex and common disease of dairy cattle and a major source of economic losses to the dairy ......
Hyperbaric oxygen intervention reduces secondary spinal cord injury in rats via regulation of HMGB1/
Objective: To investigate the impact of hyperbaric oxygen intervention(HBO)on the expressions of inflammatory cytokines ......
BACKGROUND: Polymyositis (PM) is a kind of autoimmune diseases, causing severe muscle disorders but still lacks effectiv......
The production mechanism and immunosuppression effect of pulmonary surfactant protein D via toll lik
Objective To observe the production mechanism of surfactant protein D(SP-D)in human corneal epithelial cells(HCECs)when ......
Neuroinflammation involving both astrocyte and microglia mediates mechanical allodynia induced by in
Objective Cancer pain, especially bone cancer pain, affects the life quality of cancer patients, and current treatments ......
Upregulation of cystathionine β-synthetase by toll-like receptor 4 activation contributes to viscera
Background:Irritable bowel syndrome (IBS) is a common gastrointestinal disorder characterized by abdominal pain and bloa......
背景：周期性机械牵拉是机械通气诱导肺损伤的一个重要的病因学元素,同时机械牵拉中细胞因子的变化引起远端肺组织渗透性的改变从而......
Toll-like receptor 4 signaling in neurons of trigeminal ganglion contributes to pain induced by acut
Pain caused by acute pulpitis(AP)is a common symptom in clinical settings.However,its underlying mechanisms have largely......
Previous results have shown rhCNB promoted cytokines production and stimulated the expression of the surface molecules a......
Background: Intermittent hypoxia(IH),a typical character of obstructive sleep apnea(OSA),is related to atherogenesis.How......
Disulfide-containing High Mobility Group Box-1 is Involved in Depressive-like Behavior by Activating
Depression disorder is a common,chronic and life debilitating mental illness and its mechanism remains unclear.Our previ......
Lack of association of TLR4 polymorphisms with susceptibility to rheumatoid arthritis and ankylosing
[Objective] The aim of the study was to determine whether the toll-like receptor 4 (TLR4) polymorphisms confer susceptib......
The immunostimulatory effects and pro-apoptosis activity of rhCNB against LLC is mediated by Toll-li
Recombinant human calcineurin B subunit(rhCNB)has been shown to be an immune-stimulatory protein promoting cytokine prod......
MD2 mediates Angiotensin Ⅱ-induced cardiac inflammation and remodeling via directly binding Ang Ⅱ an
Objective: We hypothesize that MD2 plays an essential role in Ang Ⅱ-induced cardiac inflammation and remodeling,and inh......
鸦片用于镇痛有上千年的历史；同时，鸦片滥用和成瘾带来非常严重的健康和社会问题。关于鸦片的研究主要围绕神经元，占中枢神经系统90％的......
Interventional effect of prostaglandin E1 on the expression of Apaf-1 and TLR4 in the rats with cere
The present study aimed to observe the interventional effect of prostaglandin E1 on the expression of Apaf-1 and TLR4 in......
Toll-like receptor (TLR) 4-mediated signaling has been shown to be important to tumor cell survival,invasion and metasta......
Aims Oxidized low density lipoprotein (ox-LDL) have been shown to exert proinflammatory effects via increasing (TLR4)-de......
Drug addiction is a serious problem,which causes serious medical and social problems.Currently there is no effective way......
Dual-color immunofluorescent labeling of diabetesassociated proteins AR and TLR4 with quantum dots i
As a new type of nanosized fluorophore,quantum dots (QDs) have been widely recognized in imaging applications and have b......
Toll-like Receptor 4 Signaling Pathway in the Protective Effect of Pioglitazone on Experimental Immu
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Mycophenolate mofetil affects monocyte Toll-like receptor 4 signaling during mouse renal ischemia/re
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Th1 immunity is not required for the effect of lipopolysaccharide exposure on modifying asthmatic re
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Calcineurin B subunit(CnB)is the regulatory subunit of calcineurin,a Ca2+/calmodulin(CaM)dependent serine/threonine ......
目的：检测ToU样受体4（TLR4）在阿尔茨海默病（AD）及血管性痴呆（VaD）患者外周血单核细胞的表达情况．探讨TLR4在老年期痴呆发病机制中的可能作......
TLR4 Knockout Attenuates BDL-induced Liver Cholestatic Injury through Amino Acid and Choline Metabol
The exact mechanism by which knockout of Toll-like receptor 4(TLR4)attenuates the liver injury remains unclear.The prese......
目的 探讨Rho激酶抑制剂对内毒素血症小鼠肾损伤的影响及其分子生物学机制.方法 将成年雄性C57BL/6小鼠随机分成对照组、脂多糖(LP......
目的观察大鼠液压冲击脑损伤Toll样受体4(TLR4)表达变化，探讨其与神经功能的关系。方法成年雄性SD大鼠56只，随机分为损伤组(n＝48)和假......
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Objective: To investigate the effects of-2242, -1892 and -1837 single nucleotide polymorphisms (SNPs) on toll-like recep......
肝胆管结石病属于肝胆疾病中常见疾病之一.已证实胆道感染、胆汁淤积、上皮间质转化是该疾病发生发展的重要因素,近年来有研究发现......
目的研究孕激素在子痫前期(preeclampsia,PE)孕妇Toll样受体4(toll-like receptor4,TLR4)-髓样细胞分化蛋白88(myeloid differenti......
Toll样受体4(TLR4)是TLRs家族的成员之一,是研究最早、最为明确的TLR分子,能够识别多种配体,通过髓样分化蛋白88依赖性信号通路诱......
Toll样受体4（TLR4）是一种模式识别受体，可以通过识别并结合相应的病原相关分子模式引发机体的固有免疫应答，诱导炎症反应。在神经系统......
目的 观察不同预后重症脓毒症患者外周血单核细胞Toll样受体4(TLR4)的表达与内毒素耐受之间的关系.方法 选取35例重症脓毒症患者(......
OBJECTIVE: To investigate the protective effects and underlying mechanism of Qingdu decoction(QDD) on experimental rats ......
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Flavonoids from Scutellaria barbata inhibit activation of tumor-associated macrophages by blocking t
OBJECTIVE:To determine the efficacy of Scutellaria barbata flavonoids and polysaccharides on Ishikawa endometrial carcin......
